Noakhali Science and Technology University

Phone: 02334496522 Fax: 02334496523 registrar@office.nstu.edu.bd
50 years of bangladesh logo Mujib 100 Logo

Department of Biotechnology and Genetic Engineering

Academic Profile of Md. Shahadat Hossain

Md. Shahadat Hossain

About Md. Shahadat Hossain


Google Scholar link: https://scholar.google.com/citations?user=vTpJhPQAAAAJ&hl=en#
ResearchGate link: https://www.researchgate.net/profile/Md_Hossain587


1. Verma AK*, Ahmed SF, Hossain MS*, Bhojiya AA, Upadhyay SK, Srivastava AK, Singh N, Harina, Rahaman MM, Bahadur NM. Unlocking SGK1 inhibitor potential of bis-[1-N,7-N, pyrazolo tetraethoxyphthalimido{-4-(3,5-Dimethyl-4-(spiro-3-methylpyazolo)-1,7-dihydro-1H-dipyrazolo[3,4-b;4',3'-e]pyridin-8-yl)}]p-disubstituted phenyl compounds: a computational study. J Biomol Struct Dyn. 2021 Oct 25:1-20. doi: 10.1080/07391102.2021.1988711. Epub ahead of print. PMID: 34696688. ( Corresponding Author) 

2. Hossain MS, Tonmoy MIQ, Fariha A, Islam MS, Roy AS, Islam MN, Kar K, Alam MR, Rahaman MM. Prediction of the Effects of Variants and Differential Expression of Key Host Genes ACE2TMPRSS2, and FURIN in SARS-CoV-2 Pathogenesis: An In Silico Approach. Bioinform Biol Insights. 2021 Oct 26;15:11779322211054684. doi: 10.1177/11779322211054684. PMID: 34720581; PMCID: PMC8554545.

3.  Hossain MS, Alam S, Nibir YM, Tusty TA, Bulbul SM, Islam M, Hossain MS. Genotypic and phenotypic characterization of Streptococcus mutans strains isolated from patients with dental caries. Iran J Microbiol. 2021 Aug;13(4):449-457. doi: 10.18502/ijm.v13i4.6968. PMID: 34557272; PMCID: PMC8421573.

4. Saha O, Islam I, Shatadru RN, Rakhi NN, Hossain MS, Rahaman MM. Temporal landscape of mutational frequencies in SARS-CoV-2 genomes of Bangladesh: possible implications from the ongoing outbreak in Bangladesh. Virus Genes. 2021 Oct;57(5):413-425. doi: 10.1007/s11262-021-01860-x. Epub 2021 Jul 12. PMID: 34251592; PMCID: PMC8274265.

5. Ahmed F, Islam MA, Kumar M, Hossain M, Bhattacharya P, Islam MT, Hossen F, Hossain MS, Islam MS, Uddin MM, Islam MN, Bahadur NM, Didar-Ul-Alam M, Reza HM, Jakariya M. First detection of SARS-CoV-2 genetic material in the vicinity of COVID-19 isolation Centre in Bangladesh: Variation along the sewer network. Sci Total Environ. 2021 Jul 1;776:145724. doi: 10.1016/j.scitotenv.2021.145724. Epub 2021 Feb 9. PMID: 33652314; PMCID: PMC7870435.

6. Verma AK, Ahmed SF, Hossain MS, Bhojiya AA, Mathur A, Upadhyay SK, Srivastava AK, Vishvakarma NK, Barik M, Rahaman MM, Bahadur NM. Molecular docking and simulation studies of flavonoid compounds against PBP-2a of methicillin-resistant Staphylococcusaureus. J Biomol Struct Dyn. 2021 Jul 9:1-17. doi: 10.1080/07391102.2021.1944911. Epub ahead of print. PMID: 34243699.

7. Hossain MS, Quadery Tonmoy MI, Islam MN, Islam MS, Afif IK, Singha Roy A, Fariha A, Al Reza H, Bahadur NM, Rahaman MM. MicroRNAs expression analysis shows key affirmation of Synaptopodin-2 as a novel prognostic and therapeutic biomarker for colorectal and cervical cancers. Heliyon. 2021 Jun 19;7(6):e07347. doi: 10.1016/j.heliyon.2021.e07347. PMID: 34195444; PMCID: PMC8239731.

8.  Kar K, Fariha A, Hossain MS*, Tonmoy MIQ, Hami I, Roy AS, Shakil MSK, Reza SK, Bahadur NM, Rahaman MM*. Prediction of Novel miRNA Biomarker Candidates for Diagnostic and Prognostic Analysis of STAD and LIHC: An Integrated in silico Approach. 2021. https://doi.org/10.1016/j.imu.2021.100581. Informatics in Medicine Unlocked. (Corresponding Author)

9. Hossain MS, Pathan AQMSU, Islam MN, Tonmoy MIQ, Rakib MI, Munim MA, Saha O, Fariha A, Reza HA, Roy M, Bahadur NM, Rahaman MM. Genome-wide identification and prediction of SARS-CoV-2 mutations show an abundance of variants: Integrated study of bioinformatics and deep neural learning. Inform Med Unlocked. 2021;27:100798. doi: 10.1016/j.imu.2021.100798. Epub 2021 Nov 18. PMID: 34812411; PMCID: PMC8598266.

10. Roy AS, Tonmoy MIQ, Fariha A, Hami I, Afif IK, Munim A, Alam MR, Hossain MS*(2020). Multi-epitope Based Peptide Vaccine Design Using Three Structural Proteins (S, E, and M) of SARS-CoV-2: An In Silico Approach. https://doi.org/10.1101/2020.06.13.149880. Journal of Applied Biotechnology Reports 2021. ( Corresponding Author)

11.  Rabbi MF, Hami I, Islam MK, Akter T, Hossain MS*, Rahaman MM*. COVID-19 Pandemic in South Asia: Challenges and Mitigation. Discoveries Reports, 2021; 4: e18. DOI: 10.15190/drep.2021.3 (Corresponding Author) 

12.  Hossain MS, Hami I, Sawrav MSS, Rabbi MF, Saha O, Bahadur NM, Rahaman MM. Drug Repurposing for Prevention and Treatment of COVID-19: A Clinical Landscape. Discoveries (Craiova). 2020 Dec 16;8(4):e121. doi: 10.15190/d.2020.18. PMID: 33403227; PMCID: PMC7758544. 

13. Hossain MS, Roy AS, Islam MS. In silico analysis predicting effects of deleterious SNPs of human RASSF5 gene on its structure and functions. Sci Rep. 2020 Sep 3;10(1):14542. doi: 10.1038/s41598-020-71457-1. PMID: 32884013; PMCID: PMC7471297.

14. Saha O, Hossain MS, Rahaman MM. Genomic exploration light on multiple origin with potential parsimony-informative sites of the severe acute respiratory syndrome coronavirus 2 in Bangladesh. Gene Rep. 2020 Dec;21:100951. doi: 10.1016/j.genrep.2020.100951. Epub 2020 Nov 1. PMID: 33163695; PMCID: PMC7603978. 

15. Shehab MA, Mahmood T, Hasanat MA, Fariduddin M, Ahsan N, Hossain MS, Hossain MS, Jahan S. A rare variety of congenital adrenal hyperplasia with mosaic Klinefelter syndrome: a unique combination presenting with ambiguous genitalia and sexual precocity. Endocrinol Diabetes Metab Case Rep. 2018 Oct 13;2018(1):18-0108. doi: 10.1530/EDM-18-0108. PMID: 30328339; PMCID: PMC6198180.

Conference proceedings:

1. Selim S, Alam SMK, Hossain MS, Hossain MS (2019). Higher level of astrocyte elevated gene 1 expression in peripheral blood monocytes in adults with newly diagnosed type 2 diabetes. 21st European Congress of Endocrinology. European Society of Endocrinology.

 2. Habib MA, Hossain MS, Hossain MS, Rahman QB (2018). A Tumor Suppressive Role of Eif3e/INT6 Gene in Oral Squamous Cell Carcinoma. 10th Asian Federation of Biotechnology Regional Symposium.

NCBI Sequence Publication:

 1.  3 partial sequences of 16S ribosomal RNA genes of different bacteria from diseased silver carp: Accession numbers are from MN658386 to MN658388

Experiences and Activities

1. Current Position:

Designation: Assistant Professor ( September  12, 2020 to date)
Department: Dept. of Biotechnology and Genetic Engineering
Institution:  Noakhali Science and Technology University

Designation: Focal Point ( July 1, 2021 to date)
Lab: Computational Biology and Chemistry Lab
Institution: Noakhali Science and Technology University 


2. Positions Held:

Assistant Provost ( October 14, 2019 to July 31, 2021), Bir Muktijoddha Abdul Malek Ukil Hall, Noakhali Science and Technology University

Co-coordinator, ( May 11, 2020 to July 31, 2021), Covid-19 detection lab,  Dept. of Microbiology, Noakhali Science and Technology University

Lecturer ( 12th Sept., 2018 to 11th Sept, 2020): Dept. of Biotechnology and Genetic Engineering, Noakhali Science and Technology University

Lecturer (30th May, 2018 to 11th September, 2018): Department of Biochemistry, Primeasia University, Dhaka, Bangladesh.

Research Associate (1st August, 2017 to 29th May, 2018): Center for Advanced Biomedical Research, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.


3. Academic Achievement:

i) “National Science and Technology (NST) Fellowship” by the Ministry of Science and Technology, People’s Republic of Bangladesh (2016)

ii) Scholarship for outstanding result in B.Sc. by Directorate of Secondary & Higher Education, Ministry of Education (2016)

iii) University Pre-Honors Scholarship, University of Dhaka (2015)

iv) Best Ambassador at Bangladesh International Conference for Biomedical Students & Young doctors (2016)

v) Board Scholarship for result in Higher Secondary Certificate Exam (2011)

vi) Board Scholarship for result in Secondary School Certificate exam (2009)


4. Training Program:

i) Training program on “Advanced Training on Biotechnology” (10th November to 19th November, 2018) organized by National Institute of Biotechnology (NIB).

ii) Workshop on “Research Methods and Statistical Analysis using STATA and Eviews” (9th August to 11th August, 2018) organized by Institutional Quality Assurance Cell (IQAC).

iii) Workshop on “Teaching-Learning Pedagogy” (28th November) organized by Institutional Quality Assurance Cell.

iv) Workshop on “University Rules and Regulations” (29th November) organized by Institutional Quality Assurance Cell.


5. Poster Presentation:

i) Best Poster Presenter at 10th Asian Federation of Biotechnology Regional Symposium (2018)
 Title: Purification and Characterization of Thuricin J1, a New Bacteriocin Produced by Bangladeshi Strain of Bacillus thuringiensis

ii) Champion at "Biotechnology-based innovative approaches for national development" competition (2016)
 Title: Go Green, Get Algae

iii) Champion at Biotech Based Business Idea Presentation Competition (2014)
 Title: Nature Agar Industries


Research Grant: 

i) Principal Investigator, Project: miRNA- based identification and validation of Differentially Expressed Genes (DEGs) partially regulating cervical and colorectal cancers, funded by Ministry of Science and Technology under Research and Development Program. (2020-2021).

ii) Project Director, Project: Development of Effective Diagnostic Tool using Allele Specific Primer to Identify Metformin Response in Bangladeshi Type II diabetic Patients, funded by Ministry of Science and Technology under Research and Development Program.

iii) Principal Investigator, Project: Isolation, characterization and detection of resistant genes of multi-drug resistant bacteria collected from waste water disposals of hospitals, funded by Research Cell, Noakhali Science and Technology University.

iv) Principal Investigator, Project: Isolation and Identification of Bacteriocin-Producing Oral Streptococci, funded by Research Cell, Noakhali Science and Technology University.  

v) Principal Investigator, Project: In silico prediction of the structural and functional modification of human tumor-suppressive RASSF5 protein, funded by Research Cell, Noakhali Science and Technology University

vi) Co-Principal Investigator, Project: Development of low cost PCR based detection technique for White Spot Syndrome Virus in cultured and wild Panaeus monodon and other crustaceans in Bangladesh, funded by Research Cell, Noakhali Science and Technology University